Public Health Evaluations

Public Health Evaluation (PHE) is hypothesis-driven research that is intended to compare one program model, approach, or intervention to another on the expected outputs, outcomes, or impacts of the program. PHEs typically address a question applicable to a broader audience and produce generalizable knowledge that can be applied more broadly—to a country, geographic region, epidemic pattern, or globally—for the scale-up or improvement of HIV and PEPFAR programs.

Two PHEs are planned for 2010-2011 in Uganda:

Early mortality reduction study
The study will evaluate the efficacy of enhanced TB case-finding to reduce six-month mortality and morbidity among patients with advanced HIV disease presenting for care at HIV clinics. This is a multi-country protocol that will be conducted at more than 40 sites.

A Virological Assessment of Walter Reed-Supported PEPFAR Program Participants on Antiretroviral Therapy
The primary objective is to estimate the proportion of program participants on ART for at least 6 months who achieve viral load suppression. Viral suppression is defined as < 400 copies/ml.