This protocol is implemented by MUWRP in collaboration with Makerere University College of Veterinary Medicine Animal Resources and Bio-security (COVAB) of Makerere University; Makerere University School of Public Health, Nature Uganda; Uganda Virus Research Institute (UVRI), Ministry of Health (MoH); US Army Medical Research Unit-Kenya (USAMRU-K);  NIAID Center of Excellence for Influenza Research and Surveillance (CEIRS) Program and WHO Reference centre on ecology of animal influenza viruses at  St. Jude Children’s Research Hospital, Memphis, USAThe Henry M. Jackson Foundation. The program receives support from the DoD-GEIS and NIH.NIAD though St Jude.

The surveillance activities are part of laboratory based influenza surveillance networks around the world, which serves to 1) detect local influenza outbreaks, 2) provide isolates for the WHO vaccine pool for vaccine component and 3) detect any emerging strains that could be pandemic potential. The surveillance has human component that collects samples from humans and non-human component that collects samples from water fowls, domestic fowl and swine.

Human samples (nasal and oral) are collected from sentinel sites at hospitals from patients who meet the inclusion criteria. The sites include Mulago national Referral Hospital, Jinja Regional Referral Hospital, and Gulu Regional Referral Hospital.

The Non-Human samples are collected from waterfowl (migratory birds) on a monthly basis from two sites; along the Lake Victoria basin and from the live bird market from the central region.